The Hellenic Society of Alzheimer’s Disease and Related Disorders (Alzheimer Hellas), the World Olive Center for Health, and Yanni’s Olive Grove are honored to announce the publication of the first global MICOIL pilot study of Greek researchers and clinicians of physicians which was published in the Journal of Alzheimer’s Disease under the title: “Randomized clinical study of early harvest extra virgin olive oil with high phenolic content in Mild Mental Disorder – MICOIL Pilot Study”.
In particular, a long-term diet rich in early-harvest extra virgin olive oil – EVOO oil rich in phenols and especially oleocanthal, perhaps starting at a young age, protects against Alzheimer’s disease, as the results of the MICOIL study showed, and is a protective shield against Alzheimer’s disease and mild mental disorder.
In the context of this work, scientists from the Department of Medicine of AUTH and the Hellenic Society of Alzheimer’s Disease and Related Disorders investigated for the first time the effect of Greek high phenol content early harvest extra virgin olive oil versus medium phenol content extra virgin olive oil – and the Mediterranean Nutrition as a natural treatment for amnesic-type mild mental disorder. In addition, genetic predisposition (APOE ε4) to Alzheimer’s disease was examined and extensive neuropsychological assessments were performed at baseline and after 12 months.
Amnesic-type mild mental disorder is usually a precursor to Alzheimer’s disease and is characterized by memory loss and an inability to perform complex activities of daily living. While there is no cure for mild mental disorder and Alzheimer’s disease (other than symptomatic treatment of Alzheimer’s disease), the global effort against mental disorders is focused on early detection and management of Alzheimer’s disease in the amnesic stage of mild mental disorder.
A long-term intervention with a Mediterranean diet rich in extra virgin olive oil (50 ml daily) in 285 study participants with high vascular risk resulted in better cognitive function compared to the control diet group. The MICOIL study showed that long-term intervention with high-phenolic early-harvest extra virgin olive oil or medium-phenolic extra-virgin olive oil was associated with a significant improvement in cognitive functions compared to the Mediterranean Diet, regardless of the presence of APOE ε4.
At the second assessment after 12 months of follow-up, the study revealed better performance in the treatment group compared to the control group. “Until today, there is no other study that has examined in such a detailed way the effects of extra virgin olive oil on elderly people with Mild Mental Disorder as an effective solution for mental impairment”, says Professor of the Department of Medicine of AUTH, Magda Tsolaki.
The scientific team consists of the Professor of the Department of Medicine of the AUTH, Magda Tsolaki, and the researchers: Eftychia Lazarou, Machi Kozori, Niki Petridou, Irini Tabaki, Iulietta Lazarou, Maria Karakota, Iordani Saulidi, Eleni Melliou, as well as Dr. Professor of the Department of Pharmacy of EKPA, Prokopio Mayati. The sponsoring company of all the extra virgin olive oils was “Yanni’s Olive Grove” of the Ioannis Prodromos family from Nea Potidaia, Halkidiki.
More information about the work in the links:
01. Magda Tsolaki
Principal scientific research officer in the MICOIL study
Professor of the 1st Department of Neurology, AUTH
President of the Hellenic Panhellenic Federation of Alzheimer’s Disease
Scientific manager of the Day Centers of the Hellenic Society of Alzheimer’s Disease and Related Disorders in Thessaloniki (Alzheimer Hellas).
Tel: +306942918933, +302310234239,
Fax: +30 2313 307332
02. Dr. Eleni Melliou
President of the Global Olive Center for Health (World Olive Center for Health)
Tel: +30 2107274052
Mob: +30 6972634077
03. Evi Psounou Prodromou
General manager of the sponsoring company Yanni’s Olive Grove
General Secretary of the Panhellenic Federation of Alzheimer’s Disease and Related Disorders
Member of the Board of the Hellenic Society of Alzheimer’s Disease and Related Disorders (Alzheimer Hellas).
Tel: +30 2373 043124
Mob: +30 6984 632200
Source: Νέα Μουδανιά Blog